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Most recent 15 results returned for keyword: necrotizing fasciitis (Search this on MAP)

https://plus.google.com/110846274964870695010 Alex Alexander : Importance of the narrow spectrum antimicrobial and conserving the viability of the intestinal indigenous...
Importance of the narrow spectrum antimicrobial and conserving the viability of the intestinal indigenous flora.

There is no better example about how much we depend of the integrity and viability of our indigenous and normal flora to avoid colonization and invasion for pathogens organisms than the relation between Clostridium difficile and using broad-spectrum antimicrobial therapy.
The colon is the home of hundreds of different genera of bacteria that start to colonize their habit just few hours later of our birth. The whole inner surface of the colon is covered by aerobes and anaerobes bacteria, attached to the mucous layer of the colon create a friendly environment for all of them, a balance that allow them survive and interact with our own cells and immune system in a amazing symbiotic way. Aerobes and anaerobes bacteria have learned to live together, resisting their own secretions and sharing nutrients.
Our daily diet constantly contribute to this internal balance with macronutrients cleaving to micronutrients used by some of them and their waste products used by others. In just one example to show our relation with them, is how the vitamin K is synthesized by the normal flora organisms and we absorb and use it to our benefit... it is our first and main source of vitamin K.
Clostridiums spp (spp = species) are an important part of our anaerobic population of normal flora, they are Gram positive rods spores formers with a high capability to synthesize and secrete toxins, no all of them are pathogens but opportunistic pathogens that can produce an invasive infections if the primary immune defense is compromised, just like wounds on the surface of the mucous layer gaining an entryway to internal structures and blood flow.
Clostridiums also are known because their most famous members produce lethal toxins; Clostridium botulinum a well known bioterrorism agent, especially its toxin. Other members like Clostridium tetani is a very important cause of mortality in developing countries and Clostridium perfringens the causal agent of necrotizing fasciitis, a entity, characterized for extensive destruction of subcutaneous and muscular tissue.
But here is a member that can be part of our normal intestinal flora in a very small portion of people and be part of this internal balance. Clostridium difficile just like its brothers, is a very capable toxin producer organism but also an opportunistic under control of the whole indigenous intestinal flora.
A clinical entity called Antibiotic-Associated Diarrhea has its main primary cause in the C. difficile, a iatrogenic disruption of the internal balance of our indigenous intestinal flora.

After 48 hours of a patient been admitted in an hospital, a large portions of their body and mucous cavities get colonized for non-indigenous organisms, some of them pathogens trying to gain a spot between all the normal flora, breaking the previous balance. Many of them can not reach their goal, but the constant exposure to highly capable opportunistic pathogens and highly resistant healthcare-associated strains finally change the balance.
The constant use of broad-spectrum antimicrobials as empirical option during the patient admission wipeout a large members of the indigenous flora, especially from the mucous cavities as the mouth, intestine and vagina, facilitating the colonization by pathogens organism commonly found in healthcares facilities.
C. difficile is one of them, but also if it is already a member of the normal intestinal flora of the patient and bearing the gene encoding the toxin production, the disruption of the balance facilitate the derepression of the gene and start the toxin production.
Patient admitted also can acquire the organism from the facility, through contact with contaminated fomites and surfaces colonizing the colon after their ingestion.

The disruption of the balance created by the indigenous flora, is the main cause of the colonization and production of the toxin by C. difficile, also some strains of this organism can colonize but not bearing the toxin gene, the clinical condition Antibiotic-Associated Diarrhea won’t be present, due is the toxin production more than just the presence of the organism is the real causal agent.

There are treatment options for this clinical entity, antibiotics like Metronidazole is one of our therapeutic option for these patients, but in the same time, been Metronidazole a highly potent anti-anaerobes drug, more members of our indigenous flora will be affected.

A rational and highly customized antimicrobial therapy is recommended when to initiate empirical antimicrobial treatment is necessary. Communication and teamwork with the clinical pharmacy and microbiology department is one of the components to achieve the final goal to avoid complications of the clinical patient picture and to avoid the emergence of resistant strains been part of the healthcare facility environment.
https://lh6.googleusercontent.com/-dJPePwxVD-4/UZ0PKmq5bmI/AAAAAAAABV8/w3C8kjGBiDc/w506-h750/david-phillips-scanning-electron-micrograph-of-clostridium-difficile-magnified-x16-000.jpg
2 days ago - Via Google+ - View -
https://plus.google.com/111415635842600902082 Disabled World : Necrotizing fasciitis is a rapidly progressing type of infection that mainly affects the subcutaneous...
Necrotizing fasciitis is a rapidly progressing type of infection that mainly affects the subcutaneous connective tissue planes or, 'fascia,' where it can quickly spread to involve adjacent soft tissues and lead to widespread tissue death or, 'necrosis.'
Necrotizing Fasciitis - Information Symptoms and Treatment
Necrotizing fasciitis usually appears as an area of localized redness, swelling, warmth and pain often resembling a superficial skin infection
3 days ago - Via Google+ - View -
https://plus.google.com/113256493817901278064 michael kaminsky : A $240,000 robotic prosthetic was given to a flesh-eating bacteria victim for no cost. Good job, #touchbionics...
A $240,000 robotic prosthetic was given to a flesh-eating bacteria victim for no cost. Good job, #touchbionics  !

"Aimee Copeland, a 25-year old Georgia graduate student, was infected with a rare flesh-eating disease, Necrotizing fasciitis, caused by Aeromonas hydrophila bacteria. Copeland contracted the bacteria in an accident while zip-lining across the Little Tallapoosa River in Georgia, May 1, 2012. The infection started after she cut her leg and got 20 stitches for it.

Three days later she was rushed to the hospital and diagnosed with necrotizing fasciitis. The doctors were forced to amputate her hands, left leg and right foot due to the fast spreading bacteria, which would have proved fatal otherwise."
https://lh4.googleusercontent.com/-4gfjCInlG5w/UZoNuHia_vI/AAAAAAAAGoU/bWTMCf36dag/w506-h750/new-240-000-bionic-hands-for-flesh-eating-bacteria-victim-at-no-cost.jpg
4 days ago - Via Google+ - View -
https://plus.google.com/118227345734170692006 Fox 35 WOFL Orlando : A metro Atlanta woman who lost both hands, her left leg and right foot after contracting a flesh-eating...
A metro Atlanta woman who lost both hands, her left leg and right foot after contracting a flesh-eating disease was on her way back from Ohio Friday after being fitted with prosthetic hands.

Aimee Copeland, 25, contracted a rare infection called necrotizing fasciitis in May 2012 after falling from a zip line and gashing her leg. She spent two months at the Shepherd Center, a rehabilitation clinic in Atlanta, learning to move, eat and bathe without prosthetics.
Flesh-eating disease victim gets prosthetic hands

4 days ago - Via Google+ - View -
https://plus.google.com/107973694480712326497 Muhammad Sudhir Raja : She fell and got a gash in her leg that required 22 staples to close. Three days later, still in pain...
She fell and got a gash in her leg that required 22 staples to close.
Three days later, still in pain, she went to an emergency room, and doctors eventually determined she had necrotizing fasciitis caused by the flesh-devouring bacteria Aeromonas hydrophila.
Doctors performed amputations to save her life.
She lost parts of all limbs: her hands, a leg and a foot.
After ravages of flesh-eating bacteria, Aimee Copeland uses new bionic hands
Flesh-eating bacteria patient Aimee Copeland now uses the latest technology in prosthetic hands to chop vegetables and pick up tiny items like Skittles.
5 days ago - Via Google+ - View -
https://plus.google.com/101058673307596154275 Janet Grace Ortigas :

Necrotizing Fasciitis Kills One in Four
Necrotizing fasciitis is sometimes called “flesh eating disease.” It is a rare bacterial infection that rapidly destroys the body’s soft tissue covering the muscles caused by more than one type of ...
6 days ago - Via Google+ - View -
https://plus.google.com/105795631871923300625 Pedro Adao :

Cancer Drug Linked to Flesh-Eating Disease - Intellihub.com
Health Canada has issued warnings to the general public and to healthcare professionals that the cancer treatment drug Avastin has been linked to necrotizing fasciitis, an infection commonly known as flesh-eating disease.
6 days ago - Via Google+ - View -
https://plus.google.com/101112206043779560751 Shezaan Shaikh :

8 days ago - Via Google+ - View -
https://plus.google.com/103678457708966446212 Elaine Radford : the spider has been cleared...

the spider has been cleared...
Slayer Guitarist Cause Of Death Report Clears Spider
Slayer guitarist Jeff Hanneman died unexpectedly at age 49, raising questions about the cause of the sudden death earlier this month just when he seemed to be recovering from a two-year battle with necrotizing fasciitis, popularly known as the flesh-eating bacteria. The death was especially frightening because the original source of the infected wound was a spider bite on his arm that went unnoticed and untreated until it was too late. On Thursda...
13 days ago - Via Google+ - View -
https://plus.google.com/105294622501132362595 Ann Ezelius :

Slayer guitarist Jeff Hanneman died of alcohol-related cirrhosis - not flesh eating disease caused by spider bite
Slayer guitarist Jeff Hanneman's cause of death has been established by a coroner as alcohol-related cirrhosis of the liver – and not as a result of flesh-eating disease Necrotizing fasciitis as previously reported.
13 days ago - Via Google+ - View -
https://plus.google.com/107095763141566419600 Mystic Metal : News: We've just learned that the official cause of Jeff Hanneman's death was alcohol related cirrhosis...
News: We've just learned that the official cause of Jeff Hanneman's death was alcohol related cirrhosis. While he had his health struggles over the years, including the recent Necrotizing fasciitis infection that devastated his well-being, Jeff and those close to him were not aware of the true extent of his liver condition until the last days of his life. Contrary to some reports, Jeff was not on a transplant list at the time of his passing, or at any time prior to that.  In fact, by all accounts, it appeared that he had been improving – he was excited and looking forward to working on a new record.
Slayer

15 days ago - Via Google+ - View -
https://plus.google.com/114399073109813320005 Richard Molby : Now you can find out your symptoms match necrotizing fasciitis while you're on the go!
Now you can find out your symptoms match necrotizing fasciitis while you're on the go!
WebMD for Android
24/7 access to health information and decision-support tools.WebMD for Andr...
15 days ago - Via Reshared Post - View -
https://plus.google.com/104270033919224289303 Steven Lash : Understanding necrotizing fasciitis is important. Read this Satori World Medical article at http://bit.ly...
Understanding necrotizing fasciitis is important. Read this Satori World Medical article at http://bit.ly/ZFpx1M.
16 days ago - Via Google+ - View -
https://plus.google.com/111571715174221335963 The MMO Troll : Today we down some shots and jump in the pit in honor of the untimely passing of guitar god Jeff Hannemen...
Today we down some shots and jump in the pit in honor of the untimely passing of guitar god Jeff Hannemen of Slayer. He died due to a spider bite, that led to necrotizing fasciitis (that's flesh-eating bacteria) in his arm, and after enduring multiple skin grafts and nerve damage, he dies of liver failure, damaged by the antibiotics and drugs used to save him. I can't think of a more Metal way to die!

Anyway, today I praise Turbine for the upcoming "Lalia's Market" feature in LOTRO, scold Trion for slowing their pace of updates significantly, and question whether Camelot Unchained will succeed with such a heavy focus on PvP.
Massive Failure #19 - Fallen Hero
Pthppt.com is a gaming blog, with bonus gaming rants, renaissance faire articles, and a new MMORPG podcast, "Massive Failure" (now on iTunes!)
17 days ago - Via Reshared Post - View -

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